Ativan is a well-known drug from the group of benzodiazepine derivatives, that are extensively used for the remedy of a large spectrum of mental well being issues from sleeping problems to epileptic seizures. According to the instructions to be used, Ativan additionally has a calming and relaxing impact.
The drug is applicable for neurosis and anxiety states accompanied by somatic problems, insomnia and panic attacks. It additionally has an anticonvulsant and muscle relaxant impact.
PHARMACODYNAMICS AND PHARMACOKINETICS
Pharmachologic impact of Lorazepam is due to its similarity with gamma-aminobutyric acid (GABA). Lorazepam belongs to the class of benzodiazepine derivatives and affects the CNS constructions, liable for the regulation of emotional exercise (these are limbic system and hypothalamus). The drug supplies the flow of chlorine into the excited neuron, which in flip stabilizes neuron.
- sleeping drug
- muscle relaxant
Active substance is properly absorbed from the digestive tract, reaching its most focus within the patient’s blood 2 hours later.
INDICATIONS AND CONTRAINDICATIONS
Ativan is extensively used in the trendy medication for the remedy of such states and mental diseases:
- various phobias
- psychosomatic disorders
- panic attacks
- obsessive-compulsive syndrome
- mental problems related to injuries
- behavioral disorders
- sleep disorders
- headache attributable to increased emotional stress and tension
- nervousness and anxiety
- consequences of the shock experienced
- sickness and vomiting, triggered by a course of chemotherapy
Also, Ativan can be used as a part of combination therapy through the therapy of chronic alcohol habit. Sometimes, it is prescribed together with analgesic medicines to organize the sufferers for operative or diagnostic interventions.
Ativan is utilized in drugs to eliminate the signs of mental diseases:
- increased anxiety
- alcohol delirium
Ativan is a strong substance; subsequently, it is strictly forbidden to the patients, which have the next concomitant illnesses and situations:
- hypersensitivity to the lively substance or auxiliary components
- intolerance to other medication with an analogous mechanism of action
- intoxication with substances miserable the central nervous system
- breathing problems
- liver failure
- apnea syndrome
- addiction to drugs, nicotine and alcohol (except withdrawal syndrome)
- alcohol intoxication
- acute renal failure
The use of Ativan is strictly forbidden to pregnant and breastfeeding ladies. If the use of Lorazepam is critical for the mother’s well being, she ought to cease breastfeeding for the time of remedy with this drugs. Also, this medication is forbidden to the minor patients. Elderly patients must take Lorazepam with great warning and closely monitor the body’s response to the drug.
The use of Ativan can have an result on the patient’s reaction rate. Therefore, through the therapy, you want to chorus from driving and managing other advanced mechanisms and restrict the work requiring caution.
According to the directions for use, you should start the treatment with Ativan with the bottom effective dose, and the course should not be long. With a large dosage and long course, such substances could make the patient addicted. In case of abrupt withdrawal of Ativan, chances are that the patient might experience withdrawal or rebound syndrome; therefore, it is essential to stop the course by progressively decreasing the drug dose.